Glutathione (GSH) is a tripeptide that is combined with glutamic acid, cysteine and glycine and contains a sulfhydryl group. It has antioxidant and integrated detoxification effects. The sulfhydryl group on cysteine is the active group of glutathione (so glutathione is often abbreviated as G-SH), which is easy to interact with certain drugs (such as paracetamol), toxins (such as free radicals, iodoacetic acid, mustard gas, lead, mercury, arsenic and other heavy metals), and has integrated detoxification effect.
Therefore, glutathione (especially glutathione in liver cells) can participate in biotransformation, thereby converting harmful poisons in the body into harmless substances and excreting them out of the body. Glutathione also helps maintain normal immune system function
1. Detoxification: combine with poison or drug to eliminate its toxic effect;
2. Participate in redox reactions: As an important reducing agent, it participates in various redox reactions in the body;
3. Protect the activity of thiol enzymes: keep the active group of thiol enzymes-SH in a reduced state;
4. Maintain the stability of the membrane structure of red blood cells: eliminate the destructive effect of oxidants on the membrane structure of red blood cells.
Food additives
1. When added to flour products, it can play a reducing role. It not only shortens the time of making bread to one-half or one-third of the original, but also greatly improves the working conditions, and also plays the role of strengthening food nutrition and other functions.
2. Add it to yogurt and infant food, which is equivalent to vitamin C and can act as a stabilizer.
3. Stir it into the fish cake to prevent the color from deepening.
4. When added to food such as meat products and cheese, it has the effect of strengthening the flavor.
1. Clinical drugs
Glutathione drugs are widely used clinically. In addition to using its sulfhydryl group to chelate heavy metals, fluorides, mustard gas and other toxin poisoning, it is also used in hepatitis, hemolytic diseases, keratitis, cataracts and retinal diseases, etc., as a treatment or Drugs for adjuvant therapy. In recent years, western scientists, especially Japanese scholars have discovered that glutathione has the function of inhibiting HIV.
The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti-allergic effect, prevent skin aging and pigmentation, reduce the formation of melanin, improve the skin's antioxidant capacity and make the skin shiny. , GSH also has a good effect in treating corneal diseases and improving sexual function.
2. Antioxidant effect
As an important antioxidant in the body, glutathione can remove free radicals in the human body; because GSH itself is susceptible to oxidation by certain substances, it can protect the sulfhydryl groups in many proteins and enzymes in the body from being harmful Oxidation of substances, so as to ensure the normal performance of molecular physiological functions such as proteins and enzymes; the content of glutathione in human red blood cells is very large, which is of great significance for protecting the sulfhydryl groups of proteins on the red blood cell membrane in a reduced state and preventing hemolysis.
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