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| Product Name | Glabridin |
| Chemical Name | 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[6,5-f]chromen-3-yl]benzene-1,3-diol; 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol |
| Analysis | HPLC |
| CAS | 59870-68-7 |
| Molecular formula | C20H20O4 |
| Extract from | licorice |
| Sprcification | 98% |
| Storage | 2-10ºC |
| The application in cosmetics | 1. Whitening, inhibiting melanin; 2. Anti-inflammatory; 3. Antioxidation. |
Glabridin is a whitening cosmetics additive, which was the first invented by the Japanese MARUZEN company in 1989. After years of use, it shows obvious effect, good safety. So in the cosmetics industry in the world, it is known as "white gold". Glabridin is one of the good curative effect, fully functional whitening ingredients, and one of the main active components in the current international high-end whitening cosmetics. In addition to the Japanese cosmetics company, Sabinsa company in the United States is one of the production of Glabridin earlier manufacturers . In addition, Lancome, Dior, Sonia Rykiel, Chanel ,and so on, meanwhile, has been widespread use of this product. Glabridin is extracted from Glycyrrhiza glabra L., and is the best whiten active ingredient in licorice. Experiment prove that it can penetrate the skin and maintain the internal highly active, effectively restrain a variety of enzyme activity during melanogenesis, especially in inhibiting the activity of tyrosinase, achieve whitening effect and effective antioxidant. At the same time, Glabridin has effect to prevent the skin coarse , anti-inflammatory, antibacterial, and so on. In view of the above excellent effect, so Glabridin is one of the ingredients of all kinds of cosmetics (e.g., beauty cream, sunscreen, essence, lotion, shower gel, etc.),especially used in the mask in recent years.
Detailed Description
Pharmacological effects :Glabridin is one of the main flavonoids in the glycyrrhiza.It in cytochrome P450 / NADPH oxidation system shows very strong resistance to free radical oxidation, can obviously inhibit the body produced during the process of metabolism of free radical, against sensitive to oxidation of biological macromolecules (DNA), low density lipoprotein LDL and cell wall by free radicals oxidative damage, etc.In this way, certain pathological changes related to free radical oxidation can be prevented, such as atherosclerosis, cell aging and so on.In addition, the glycyrrhiza has a certain effect of lowering blood lipid and lowering blood pressure.
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